Tuesday, November 5, 2019

The human fetus is considered to be particularly sensitive to environmental contaminants. A team has now been able to demonstrate for the first time how the widespread food estrogen zearalenone behaves in the womb. Using a new analytical method, it was shown that the xenoestrogen migrates through the placenta and is partially converted to other harmful substances.


Xenoestrogens are absorbed through the environment, especially through food. As estrogen-like substances, they can have a profound effect on the body's hormonal balance. Zearalenone, a widespread food estrogen, is produced by fungi (Fusarium species) and enters the body mainly through the diet of bread, cereals and other grain-based products.

"The placental barrier offers the unborn child a certain degree of protection against bacteria, viruses and some foreign substances including some drugs or environmental toxins absorbed by the body. But, as we were able to show for the first time, zearalenone migrates through the placental barrier" says first author Benedikt Warth from the Institute of Food Chemistry and Toxicology at the University of Vienna.

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